HIV drug resistance

The ability of HIV to mutate and reproduce itself in the presence of antiretroviral drugs is called HIV drug resistance (HIVDR). The consequences of HIVDR include treatment failure and further spread of drug resistant HIV. This can compromise the effectiveness of the limited therapeutic options to reach the last 90 target (of achieving viral suppression) and further reduce HIV incidence, mortality and morbidity.

Currently, WHO is developing a new five-year global action plan for 2017-2021 to support a coordinated international effort to prevent, monitor and respond to the emergence of HIV drug resistance, and to strengthen country efforts to achieve the global HIV targets.