Intermittent preventive treatment for infants using sulfadoxine-pyrimethamine (IPTi-SP) for malaria control in Africa: implementation field guide
WHO recommends IPTi-SP for infants living in areas with moderate-to-high malaria transmission in sub-Saharan Africa. Treatment should be given three times during the first year of life at intervals corresponding to routine vaccination schedules. This intervention has been shown to reduce clinical malaria, anaemia and severe malaria in children under the age of one.
This field guide provides the necessary technical and operational information and tools to guide decisions by country-level policy-makers and programme managers around the implementation of IPTi-SP.
IPTi-SP is the administration of a full therapeutic course of SP delivered through the Expanded Programme on Immunization (EPI) at intervals corresponding to routine vaccination schedules for the second and third doses of DTP/Penta, and measles vaccination — usually at 8-10 weeks, 12-14 weeks, and ~9 months of age — to infants at risk of malaria.
- WHO Policy recommendation on intermittent preventive treatment during infancy with sulphadoxine-pyrimethamine (IPTi-SP) for Plasmodium falciparum malaria control in Africa (2010)