Maternal, newborn, child and adolescent health

The current evidence for the burden of group A streptococcal diseases

World Health Organization

Publication details

Number of pages: 52
Publication date: 2005
Languages: English
WHO reference number: WHO/FCH/CAH/05.07



Group A streptococcus (GAS) causes a broad spectrum of disease, from severe invasive infections and the post-streptococcal complications of acute rheumatic fever (ARF) and acute post-streptococcal glomerulonephritis (APSGN) to mild superficial infections of the throat or skin. This review conducts a systematic review into diseases caused by this organism and summarizes the global disease burden estimates. It looks into the quality of data, its limitations and advocates for better quality studies especially from neglected regions of the world.