Neglected tropical diseases

Preventive Chemotherapy and Transmission Control (PCT)


PCT focuses on diseases for which a strategy exists as well as on tools and the availability of safe and effective drugs that make it feasible to implement large-scale preventive chemotherapy.

The diseases include cysticercosis, dracunculiasis (guinea-worm disease), foodborne trematode infections, lymphatic filariasis, onchocerciasis, schistosomiasis and soil-transmitted helminthiasis. Blinding trachoma control through the SAFE strategy – combining drug treatment with hygiene and environmental management – can be linked to helminth control interventions to improve the overall health of affected communities.


To provide national programmes with technical guidelines that emphasize a coordinated, cost-effective approach to the implementation of national elimination and control activities where preventive chemotherapy is the main tool, i.e. regular anthelminthic drug administration to all people at risk of morbidity due to helminthic diseases, starting early in life.

  • To develop technical guidelines and tools.
  • To build capacity through development of training tools, workshops and guidelines.
  • To advocate for a coordinated approach to preventive chemotherapy.
  • To build new partnerships and expand those that already exist.

To coordinate preventive chemotherapy and transmission control global strategies in consultation with WHO country and regional offices, collaborating centres and partners from academic and research institutions, the private sector, nongovernmental development organizations, international agencies and other United Nations organizations.