TB preventive care
One third of the world’s population is estimated to have latent TB infection (LTBI); in other words, they do not have active TB disease but may develop it through a process of reactivation of dormant bacilli that start multiplying and produce active TB. The lifetime risk of reactivation for a person with documented LTBI is estimated to be 5-10%, with the majority developing TB disease within 18 months of initial infection. However, the risk is considerably higher in the presence of predisposing factors, such as HIV infection. The management of LTBI is an innovative element of the “prevention package” of WHO’s End TB Strategy.
3 out of 10persons globally are thought to have latent TB infectionLTBI factsheet
60-90%risk reduction of developing active TB with currently available treatmentLatent TB Infection: Updated and consolidated guidelines for programmatic management
5-10%of people infected with TB bacteria have a lifetime risk of developing active TB disease.LTBI Q&A
News and events
14 November 2018
Meeting of the Implementation Core Group of WHO Global Task Force on Latent TB Infection and country stakeholders on implementation tools and joint TB and HIV programming to scale up TB preventive treatment
A consultation was held with select members of the Global LTBI Task Force to discuss key strategies to achieve the UN High Level Meeting target for TB prevention, and garner input on the draft operational guidance for programmatic management of LTBI, indicators for monitoring and evaluation, and key elements for TB and HIV programming for scale-up of TB preventive services.
27 October 2017
The Global TB Programme of WHO has developed a mobile application (app) to facilitate monitoring and evaluation of programmatic management of LTBI.
31 August-1 September 2017, Seoul, Republic of Korea
A technical consultation was held to explore the challenges, barriers and prospect of existing and novel LTBI diagnostics and digital tools in the programmatic management of LTBI.
27-28 April 2016, Seoul, Republic of Korea
First global consultation on latent TB infection and review of Korea’s TB programme
WHO commends Korea's accelerated efforts to end TB
The Republic of Korea is ramping up efforts to tackle tuberculosis (TB) – a top infectious disease killer worldwide – as part of its plan to cut TB incidence by half between 2011 and 2020.